This patch will remove Lexmark and LexmarkInkjet keys from the registry at:

HKey_Current_User\Software\Classes\VirtualStore\Machine\Software

Note the registry section is HKey_Current_User  which mean the issue should not exist 
if you crate another administrator account and log on to that account.

THIS ONLY AFFECTS Vista and later systems,  XP will not have virtualization issues

Issues we have seen:
1. constant communication error,  again if you create a new account to test 
with then the communication error should not exist,  you can then delete the 
test account and run the patch 

2. intermittently you receive script errors or you send the job and it just sits 
in the queue,  again try the new account before running the patch;  
although the keys being created should not be there anyway so no harm
to run the patch.  If you create the new account and the issue still exist
this patch will more than likely not resolve the issue.

There could be other issues we do not know about that are caused by virtualization,  if you 
create a new account and the issue does not exist, then try the patch and let us know.

What is virtualization of registry keys?  When we are installing and writing registry keys 
if for any reason the the Operating System thinks it does not have the proper permissions
to write the key then it will write it in another part of the registry in an attempt to resolve 
that it can write the key(s). Then OS schema would attempt to redirect to this section
of the registry if you are accessing these keys.
operating system